Role of Bronchial Washing Gene Xpert in Sputum-Scarce Cases of Suspected Pulmonary Tuberculosis

  • Faisal Faiyaz Zuberi DUHS
  • Sagheer Hussain Dow University of Health Sciences
  • Sidra Hameed Dow University of Health Sciences
  • Bader Faiyaz Zuberi Dow University of Health Sciences
Keywords: Pulmonary Tuberculosis; Bronchoscopy; Sputum Smear; Bronchial Washing

Abstract

Objective: To determine the frequency of mycobacterium tuberculosis detection, in bronchial washing in sputum-scarce cases of suspected pulmonary tuberculosis.

Methods: A descriptive cross-sectional study was conducted at the Ojha Institute of Chest Diseases, Dow University of Health Sciences, Karachi, during July 2016 to December 2017. Sputum-scarce patients with suspicion of pulmonary tuberculosis were selected and underwent for bronchoscopy, detailed examination of bronchial tree was performed, and bronchial washing collected for testing of mycobacterium tuberculosis with Gene Xpert.

Results: A total of 120 patients were included. In this study 55 (45.8%) patients were female and 65 (54.2%) were male with mean±SD of age was 39.9±14.7 years. Bronchial washing Gene Xpert for mycobacterium tuberculosis was detected in 83 (69.2%) sputum-scarce cases of suspected pulmonary tuberculosis patients.

Conclusion: Bronchial washing Gene Xpert has an excellent diagnostic yield for detection of mycobacterium tuberculosis in sputum-scarce cases of suspected pulmonary tuberculosis.

How to cite this:
Zuberi FF, Hussain S, Hameed S, Zuberi BF. Role of Bronchial Washing Gene Xpert in Sputum-Scarce Cases of Suspected Pulmonary Tuberculosis. Pak J Med Sci. 2019;35(1):---------. doi: https://doi.org/10.12669/pjms.35.1.107

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Author Biographies

Sagheer Hussain, Dow University of Health Sciences

Ojha Institute of Chest Disease

PG Trainee

 

Sidra Hameed, Dow University of Health Sciences

Ojha Institute of Chest Dieases

PG Trainee

Bader Faiyaz Zuberi, Dow University of Health Sciences

Department of Medicine

Professor

Published
2018-12-20
Section
Original Articles