Association of anti-HCV sero-prevalence with blood transfusion and practice of haemodialysis from multiple centres in patients on maintenance haemodialysis

Association of anti-HCV sero-prevalence with blood transfusion

  • Umbreen Amjad
  • Saqib Qayyum Ahmad Bahria International Hospital
  • Saima Mir
  • Moazam Ayub
Keywords: Anti-HCV, Blood transfusion, End stage kidney disease, Maintenance haemodialysis

Abstract

Objectives: To determine the frequency of anti-HCV in patients on maintenance haemodialysis (HD) and its association with history of blood transfusion and with the practice of HD from more than one center.

Methods: All the patients on maintenance HD at Bahria International hospital (BIH) Rawalpindi from March 2019 to May 2019 were included. Demographic details, history of blood transfusions and history of HD from any other center in addition to BIH, were recorded. Anti-HCV was done by chemiluminescent assay. Chi-square was used to compare the categorical variables. Odds ratio (OR) and relative risk (RR) for the groups exposed to risk were calculated.

Results: Of 96 patients, 40 (41.6%) were anti-HCV positive. Sixty–two (64.6%) had transfusion history. Thirty-one (50%) of these 62 were anti–HCV positive as compared to 9 (26.5%) of 34 with no history of transfusion (p=0.025); OR=2.78 (p=0.0278), RR=1.89 (p=0.0420). Among 66(68.7%) of 96 who had HD from other centres in addition to ours, 33(50%) were anti-HCV positive as compared to 7(23.3%) of 23 who had HD from BIH only (p=0.014); OR=3.29 (p=0.0167), RR=2.14 (p=0.0309).

Conclusion: There was a high prevalence (41.6%) of anti-HCV in our HD patients and anti-HCV positivity had significant association with history of blood transfusion as well as with history of HD from multiple centres.

doi: https://doi.org/10.12669/pjms.36.2.1343

How to cite this:
Amjad U, Ahmad SQ, Mir S, Ayub M. Association of anti-HCV sero-prevalence with blood transfusion and practice of haemodialysis from multiple centres in patients on maintenance haemodialysis. Pak J Med Sci. 2020;36(2):286-289.
doi: https://doi.org/10.12669/pjms.36.2.1343

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published
2019-12-16
How to Cite
Amjad, U., Ahmad, S., Mir, S., & Ayub, M. (2019). Association of anti-HCV sero-prevalence with blood transfusion and practice of haemodialysis from multiple centres in patients on maintenance haemodialysis. Pakistan Journal of Medical Sciences, 36(2). https://doi.org/10.12669/pjms.36.2.1343
Section
Short Communication