Disease staging according to international scoring system in newly diagnosed patients with multiple myeloma

Disease staging in multiple myeloma

  • Saira Parveen Sheikh Liaquat National Hospital
  • Syed Muhammad Irfan, Dr. Liaquat National Hospital, Karachi, Pakistan
  • Sadia Sultan Sheikh, Dr. Liaquat National Hospital, Karachi, Pakistan
Keywords: Newly diagnosed multiple myeloma, International scoring system, disease staging

Abstract

Objective: To determine the frequency of disease staging according to international scoring system in patients who are newly diagnosed with Multiple Myeloma (MM) at a tertiary care hospital at Karachi.

Methods: This single center, non probability consecutive, cross sectional study was conducted from Nov 11, 2015 to May 11, 2016. After taking informed written consent, detailed history was taken and serum β2 microglobulin and albumin levels were checked to assess the study outcome variable i.e. stage of MM. All the collected information was entered in the prescribed performa.

Results: Eighty newly diagnosed patients with multiple myeloma as per inclusion criteria were included. Sixty seven (83.75%) were male and 13(16.25) were females, with mean age of 58.35+10.077 years. Twenty seven patients (33.75%) were found to have stage-I disease, in 23 (28.75%) stage-II and stage-III in 30 (37.5%).

Conclusion: Multiple myeloma is relatively common in 5th decade, with male predominance. International Staging System have great potential for characterizing and stratifying multiple myeloma and revealed a predominance of advanced stage III disease in our setting.

How to cite this:
Shaikh SP, Irfan SM, Sheikh SS. Disease staging according to international scoring system in newly diagnosed patients with multiple myeloma. Pak J Med Sci. 2019;35(1):90-94. doi: https://doi.org/10.12669/pjms.35.1.173

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Author Biographies

Syed Muhammad Irfan, Dr., Liaquat National Hospital, Karachi, Pakistan

Professor and head of the department in the department of Hematology at Liaquat National Hospital, Karachi, Pakistan

Sadia Sultan Sheikh, Dr., Liaquat National Hospital, Karachi, Pakistan

Assistant professor at the department of Hematology at Liaquat National Hospital, Karachi, Pakistan

Published
2019-01-22
Section
Original Articles