Biochemical profile changes in stored donor blood for transfusion

  • May AlMoshary College of medicine, Princess Nourah Bint Abdul Rehman University, Riyadh, Saudi Arabia
  • Eman Al Mussaed College of medicine, Princess Nourah Bint Abdul Rehman University, Riyadh, Saudi Arabia
  • Maria Arabdin Rehman Medical College, Peshawar
Keywords: Storage lesion, Blood transfusion, Hyperkalaemia

Abstract

Objectives: This study’s aim was to find out that how various biochemical parameters of donor blood are affected during storage.

Methods: This cross-sectional study was conducted in hematology Unit of Rehman Medical Institute, Peshawar and Fatimid Foundation, Peshawar Khyber Pakhtunkhwa, over a period of six months from June 2018 to November 2018. This study includes 300 healthy volunteer donors. Analysis of stored blood was done at 0, 3, 7, 14- and 21-days interval. Data were recorded and analyzed in SPSS v 20. A p value of less than 0.05 was taken as significant.

Results: Three hundred healthy volunteer donors were included in the study in which 63% were male and 37% were females. Mean age was 26.54±7.3 years with age range from 23-46 years. Out of 300 donors 15.33% were O+, 35.33%, 9.66% B+, 8.33% A+, 7.66% AB+, 7.66% O-, 7% A- and 9% B-. Significant. Changes were observed in serum potassium, LDH, pH, serum chloride, serum sodium and AST levels. (p:<0.001). however, storage did not affect rest of the parameters.

Conclusion: This study reveals that during storage certain changes occur in haematological and biochemical parameters which ultimately may put patients at risk.

doi: https://doi.org/10.12669/pjms.35.6.220

How to cite this:
Al-Moshary M, Al-Mussaed E, Arab-din M. Biochemical profile changes in stored donor blood for transfusion. Pak J Med Sci. 2019;35(6):1697-1700. doi: https://doi.org/10.12669/pjms.35.6.220

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Author Biographies

May AlMoshary, College of medicine, Princess Nourah Bint Abdul Rehman University, Riyadh, Saudi Arabia

Assistant professor, Haemotology department, 

 

Eman Al Mussaed, College of medicine, Princess Nourah Bint Abdul Rehman University, Riyadh, Saudi Arabia

Assistant professor, Haematology,

 

Published
2019-10-10
Section
Original Articles