Effects of structured exercise regime on Glycosylated Hemoglobin and C reactive protein in patients with Gestational Diabetes Mellitus - A randomized controlled trial

  • Wardah Ajaz Qazi Foundation University Institute of Rehabilitation Sciences, Foundation University Islamabad
  • Muhammad Naveed Babur Dean, Faculty of rehabilitation sciences, Isra University Islamabad
  • Arshad Nawaz Malik Riphah college of Rehabilitation & Allied Health sciences, Riphah International University Islamabad
  • Ruqia Begum Foundation University Institute of Rehabilitation Sciences, Foundation University Islamabad
Keywords: Aerobics, C reactive protein, Exercise, Gestational diabetes mellitus, Glycosylated hemoglobin.

Abstract

Objectives: To evaluate the effects of structured exercise regime on Glycosylated hemoglobin and C reactive protein in patients with gestational diabetes mellitus.

Methods: This two arm parallel randomized controlled trial was conducted at Fauji Foundation Hospital, Rawalpindi from November 2018 till December 2019 on the 54 diagnosed gestational diabetes mellitus patients (Dropped out=4 Analyzed= 50) with age 20 to 40 years and gestational age from 20 to 36 weeks. Selection was done via convenient sampling technique and randomized into two groups (n=25) by sealed envelope method. Structured exercise regime group received combination of moderate intensity aerobics, stabilization and pelvic floor muscles exercises twice a week for 5 weeks (40 min per session) along with dietary and medical interventions while control group received only medical and dietary interventions with postural education. Demographics, glycosylated hemoglobin and C reactive protein were recorded at baseline then after 5 weeks of intervention. Analysis was done by SPSS 20.

Results: Mean age was 35.92 ± 5.24 years in control group while 34.36 ± 5.21 years in interventional group. Between group analysis for HbA1c showed no significant difference at base line (p >0.05) but showed significant difference (p <0.05) after five weeks’ interventions. Similarly, for C reactive protein both groups showed no significant difference (p >0.05) at baseline but after five weeks of interventions showed significant difference (p<0.05).

Conclusion: Structured exercise regime helps in reducing values of glycosylated hemoglobin and C reactive protein in patients with gestational diabetes mellitus.

Trial Registration: ClinicalTrials.gov; NCT04146740.

doi: https://doi.org/10.12669/pjms.36.7.2488

How to cite this:
Qazi WA, Babur MN, Malik AN, Begum R. Effects of structured exercise regime on Glycosylated Hemoglobin and C reactive protein in patients with Gestational Diabetes Mellitus -A randomized controlled trial. Pak J Med Sci. 2020;36(7):1449-1453.  doi: https://doi.org/10.12669/pjms.36.7.2488

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Published
2020-10-17
How to Cite
Qazi, W., Babur, M., Malik, A., & Begum, R. (2020). Effects of structured exercise regime on Glycosylated Hemoglobin and C reactive protein in patients with Gestational Diabetes Mellitus - A randomized controlled trial. Pakistan Journal of Medical Sciences, 36(7). https://doi.org/10.12669/pjms.36.7.2488
Section
Original Articles