Correlation between Prenatal Fetal Hemodynamic Parameters and Growth Indices in Pregnant Women with Preeclampsia and Neonatal Ultrasound Indicators of Organ Development

Abstract

Objectives: This retrospective study aimed to explore the associations between prenatal fetal hemodynamics and growth parameters in pregnant women with preeclampsia and neonatal ultrasound assessment indicators of organ development.

Methodology: Clinical parameters of 296 pregnant women and their neonates admitted to Xi’an Fourth Hospital from December 2024 to December 2025 were collected. Those women diagnosed with preeclampsia were included in the study group (n=148). During the same period, age-matched healthy pregnant women and their neonates were included in the control group (n=148). Clinical data of prenatal and neonatal ultrasound examinations, fetal hemodynamic parameters, growth parameters, and neonatal organ development indicators were collected and analyzed.

Results: Compared with the control group, the study group had significantly lower peak systolic velocity (PSV) and end diastolic velocity (EDV) of the umbilical artery, middle cerebral artery (MCA), renal artery (RA), biparietal diameter (BPD), head circumference (HC), abdominal circumference (AC), femur length (FL), bilateral renal volume, and liver thickness (P<0.05), whereas the myocardial performance index (MPI) was higher in the study group (P<0.05). Pearson correlation analysis showed that PSV, EDV, MCA, RA, BPD, HC, AC, and FL were positively correlated with bilateral renal volume and liver thickness, and negatively correlated with MPI (P<0.05).

Conclusion: Preeclampsia was associated with insufficient fetal blood perfusion and growth retardation. Prenatal ultrasound indicators are closely related to neonatal developmental status and can be used to predict neonatal organ development.