Clinical presentations and biochemical profile in adult celiac disease patients in Hyderabad: Pakistan

Abstract

Objective: To see the various clinical presentations and biochemical profile in adult celiac disease patients of Hyderabad Sindh.

Methods: A total 60 suspected cases of adult celiac disease, both males and females were screened out from liaquat University of Medical and Health Sciences hospital and private clinics at Sadar Hyderabad Sind by non probability purposive sampling during a period from July 2011 to December 2012.Age ranged between 18 to 55 Years. A detailed history and clinical examination was done. Patients already on gluten free diet, age < 12years, tuberculosis or cancer of intestine/colon and patients of diabetes and thyroid disorder were excluded, while patients having positive ant tTG (value > 15 iu/ml detected by ELISA) were included. The biochemical profile including serum albumin, calcium ,ferritin, SGPT, Alkaline phosphatase and Haemoglobin were estimated in central Diagnostic laboratory LUMHS by taking 10 cc centrifuged blood sample. The data was plotted on SPSS 16, mean and percentages were calculated.

Results: All patients were divided in to three groups according to age. The most common group was 18-30 years; (mean, 23.5