The significance of tubular and glomerular proteinuria in critically ill patients with severe acute kidney injury

Authors

  • Christopher Thiam Seong Lim Head of Unit Nephrology
  • Han Khim Tan Senior Consultant Nephrology
  • Yeow Kok Lau Medical Scientist

DOI:

https://doi.org/10.12669/pjms.306.5684

Keywords:

Acute kidney injury, Dialysis, Electrophoresis, Proteinuria, APACHE.

Abstract

Objective: Critically ill patients with acute kidney injury (AKI) frequently need acute renal replacement therapy (aRRT). We evaluated an inexpensive, rapid quantitative and qualitative analysis of proteinuria on the course of AKI patients requiring aRRT in intensive care.

Method: This was a prospective, observational study of critically ill patients with severe established AKI or Acute on Chronic Kidney Injury (AoCKI) requiring aRRT. Urine samples were analyzed using Sodium-Dodecyl-Sulphate-Polyacryamide Gel Electrophoresis (SDS-PAGE).

Results: A total of 30 critically ill patients were studied. Those who died have higher APACHE II (29

Author Biographies

Christopher Thiam Seong Lim, Head of Unit Nephrology

Department of Medicine, Faculty of Medicine and Health Sciences ,Universiti Putra Malaysia

Han Khim Tan, Senior Consultant Nephrology

Department of Renal Medicine

Singapore General Hospital

Yeow Kok Lau, Medical Scientist

Department of Renal Medicine

Singapore General Hospital

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Published

2014-09-10

How to Cite

Lim, C. T. S., Tan, H. K., & Lau, Y. K. (2014). The significance of tubular and glomerular proteinuria in critically ill patients with severe acute kidney injury. Pakistan Journal of Medical Sciences, 30(6). https://doi.org/10.12669/pjms.306.5684

Issue

Vol. 30 No. 6 (2014): November – December 2014 Pak J Med Sci

Section

Original Articles