Low molecular weight heparin in unexplained recurrent miscarriage

Halide Yuksel; Semra Kayatas; Aysen Boza; Murat Api; Aktug Ertekin; Cetin Cam

doi:10.12669/pjms.306.5477

Authors

Halide Yuksel Zeynep Kamil Women and Children Diseases Training and Research Hospital
Semra Kayatas Zeynep Kamil Women and Children Diseases Training and Research Hospital
Aysen Boza Zeynep Kamil Women and Children Diseases Training and Research Hospital
Murat Api Zeynep Kamil Women and Children Diseases Training and Research Hospital
Aktug Ertekin Zeynep Kamil Women and Children Diseases Training and Research Hospital
Cetin Cam Zeynep Kamil Women and Children Diseases Training and Research Hospital

DOI:

https://doi.org/10.12669/pjms.306.5477

Keywords:

Enoxaparin, Tinzaparin, Live birth rate, Unexplained recurrent miscarriage.

Abstract

Objective: The aim of the study was to investigate whether the use of low molecular weight heparin (LMWH) improve live birth rates when compared with control group in patients with unexplained recurrent miscarriages (URM).

Methods: In this prospective observational study 150 women with a history of two or more previous unexplained first trimester pregnancy loss who received LMWH; either enoxaparin (n=50), tinzaparin (n=50) or nothing (n=50) were followed for the pregnancy outcome measures. Only the patients who have used standardized dosage of LMWH (4000 IU/day enoxaparin or 3500 IU/day tinzaparin ) were included to the study.