Salivary detection of human Papilloma virus 16 & 18 in pre-malignant and malignant lesions of oral cavity:Is it feasible in Pakistani context of Socio-Cultural Taboos?

Authors

  • Iqbal A. Muhammad Khyani Associate Professor Department of E.N.T, Head & Neck Surgery, Dow University of Health Sciences, Dow Medical College, Civil Hospital, Baba-e-Urdu Road, Karachi, Pakistan. Post Code; 74200.
  • Masood A. Qureshi
  • Talat Mirza
  • M. Umar Farooq

DOI:

https://doi.org/10.12669/pjms.315.7093

Keywords:

Pre-malignant lesions, Oral squamous cell carcinoma, Salivary diagnosis, Biomarkers, Human papilloma virus.

Abstract

Objective: To evaluate salivary detection of HPV-16 & 18 would be feasible and informative biomarker for oral pre-malignant and malignant lesion in our population.

Methods: This non-interventional, case control study was carried out at department of E.N.T, Head and Neck Surgery, Dow University of Health Sciences, Dow Medical College and Civil Hospital Karachi, Pakistan between July 2011 to December 2012. Total of 105 cases were recruited. These were divided in three groups

Author Biography

Iqbal A. Muhammad Khyani, Associate Professor Department of E.N.T, Head & Neck Surgery, Dow University of Health Sciences, Dow Medical College, Civil Hospital, Baba-e-Urdu Road, Karachi, Pakistan. Post Code; 74200.

Associate Professor

Department of E.N.T, Head & Neck Surgery,

Dow University of Health Sciences, Dow Medical College,

Civil Hospital, Baba-e-Urdu Road,

Karachi, Pakistan.

Post Code; 74200.

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Published

2015-10-08

How to Cite

Khyani, I. A. M., Qureshi, M. A., Mirza, T., & Farooq, M. U. (2015). Salivary detection of human Papilloma virus 16 & 18 in pre-malignant and malignant lesions of oral cavity:Is it feasible in Pakistani context of Socio-Cultural Taboos?. Pakistan Journal of Medical Sciences, 31(5). https://doi.org/10.12669/pjms.315.7093

Issue

Vol. 31 No. 5 (2015): September - October 2015 Pak J Med Sci

Section

Original Articles