Ferulic acid promoting apoptosis in human osteosarcoma cell lines

Authors

  • Xu-dong Zhang Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
  • Qiang Wu Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
  • Shu-hua Yang Department of Orthopedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China

DOI:

https://doi.org/10.12669/pjms.331.12066

Keywords:

Apoptosis, Bcl-2, Bax, Caspase-3, Ferulic acid, Procaspase-3, Osteosarcoma.

Abstract

Objective: To explore the promoting apoptosis and antitumor activities of ferulic acid (FA) in human osteosarcoma and its potential mechanism.

Methods: The SaOS-2 and MG63 osteosarcoma cell lines were opted to experiment and these cells were, respectively, cultured with various concentrations of FA (0

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Published

2017-02-22

How to Cite

Zhang, X.- dong, Wu, Q., & Yang, S.- hua. (2017). Ferulic acid promoting apoptosis in human osteosarcoma cell lines. Pakistan Journal of Medical Sciences, 33(1). https://doi.org/10.12669/pjms.331.12066

Issue

Vol. 33 No. 1 (2017): January – February 2017 Pak J Med Sci

Section

Original Articles