Comparison of pressure vs. volume controlledventilation on oxygenation parameters of obese patients undergoing laparoscopic cholecystectomy

Abstract

Background & Objective: There is no special guideline for the best ventilation mode during laparoscopic anesthesia in obese patients and there are too many studies with different controversial points. The aim of this study was to compare the effect of pressure controlled ventilation (PCV) vs. volume controlled ventilation (VCV) on respiratory and oxygenation parameters in patients undergoing laparoscopic cholecystectomy.

Methods: Seventy patients with 30 <BMI<40 and ASA physical status I-II were studied in this randomized prospective trial. Anesthesia was started with VCV and after creation of pneumoperitoneum; the patients were randomized into PCV or VCV groups. Ventilation parameters were adjusted to a CO2 target of 35-40 mmHg. Hemodynamic and oxygenation parameters and respiratory parameters like plateau, mean airway and peak pressure were recorded for all patients during the study.

Results: Patients in VCV group needed higher tidal volume and respiratory rate to maintain target CO2 in 35 and 55 minutes after the study. Plateau pressure and mean airway pressure in two groups didn