Evaluation of the children with acute acetaminophen overdose and intravenous N-acetylcysteine treatment

Authors

  • Yakup Yesil Department of Pediatrics,Kanuni Sultan Süleyman Training and Research Hospital, Medical Science University
  • Abdurrahman Avar Özdemir Department of Pediatrics, Medicine Hospital, Biruni University

DOI:

https://doi.org/10.12669/pjms.343.14937

Keywords:

Acetaminophen intoxication, N- acetylcysteine, Children.

Abstract

Objective: To evaluate the demographic and clinical features associated with acetaminophen overdose and to identify the clinical use of IV (intravenous) N- Acetylcysteine (NAC) treatment in children.

Methods: This prospective study was conducted in Kanuni Sultan Suleyman Training and Research Hospital between August 2016 and August 2017. A total of 59 patients with overdose acetaminophen ingestion were included in this study. The toxic dose for acute acetaminophen intake was defined as greater than 150 mg/kg. Rumack-Matthew nomogram was used to evaluate the risk of acute intoxication and to determine the decision of using antidote.

Results: The mean age of the patients was 8.5

Author Biographies

Yakup Yesil, Department of Pediatrics,Kanuni Sultan Süleyman Training and Research Hospital, Medical Science University

Pediatrics

Abdurrahman Avar Özdemir, Department of Pediatrics, Medicine Hospital, Biruni University

pediatrics

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Published

2018-06-11

How to Cite

Yesil, Y., & Özdemir, A. A. (2018). Evaluation of the children with acute acetaminophen overdose and intravenous N-acetylcysteine treatment. Pakistan Journal of Medical Sciences, 34(3). https://doi.org/10.12669/pjms.343.14937

Issue

Vol. 34 No. 3 (2018): May - June 2018

Section

Original Articles