Association of serum liver enzyme Alanine Aminotransferase (ALT) in patients with type 2 diabetes

Abstract

Objectives: To assess the association of raised serum liver enzyme (ALT) with type 2 diabetic subjects.

Methods: This retrospective data was accessed at Baqai Institute of Diabetology and Endocrinology (BIDE) from January 2005 to May 2016. A total of 1966 subjects with type 2 diabetes were included in the study. Subjects were divided into two groups; in group A 1284 subjects had ALT within the normal range (ALT?35iu/l) and in Group-B 682 subjects had elevated ALT (ALT>35iu/l). Details of demographics, anthropometric measurements and biochemical results at baseline were extracted from the health management system of BIDE. Data analysis was conducted on Statistical Package for Social Sciences (SPSS) version 20.

Results: Out of 1966 type 2 diabetic subjects 1284(65.4%) were observed with normal value of ALT (?35) and 682(34.6%) with elevated ALT (>35). Overall mean age of subjects was 54.66