Outcome of radioactive iodine therapy in Toxic Nodular Goiter in Pakistan

Authors

  • Tauseef Ahmad Dr Ziauddin University Hospital, North Nazimabad Campus, Karachi.
  • Adeel Khoja Aga Khan University Hospital, Karachi
  • Naveed Haroon Rashid Aga Khan University Hospital, Karachi
  • Muhammad Areeb Ashfaq Aga Khan University Hospital, Karachi

DOI:

https://doi.org/10.12669/pjms.345.15244

Keywords:

Outcome, Radioactive iodine, Single center, Toxic nodular goiter.

Abstract

Objective: To determine the outcome of patients receiving radioactive iodine therapy for toxic nodular goiter coming to Aga Khan University Hospital Karachi.

Methods: A total of 89 patients who visited the outpatient department of Aga Khan University Hospital from January 2010 to August 2017 were recruited for the study. Toxic nodular goiter was diagnosed on the basis of having hot nodule on thyroid scan with low TSH and high FT4/T4. Other demographic and laboratory data were also recorded.

Results: Eighty nine patients with toxic nodular goiter received a dose range from 10 to 30mCi RAI. Six months after RAI, 36.2% became hypothyroid, 38.5% became euthyroid while 25.3% remained hyperthyroid. Thyroid outcome at 3 months were correlating with 6 months results.

Conclusion: Radioactive iodine therapy is a safe and effective way of treating toxic nodular goiter which usually results in cure of hyperthyroidism in majority of patients.

doi: https://doi.org/10.12669/pjms.345.15244

How to cite this:Ahmad T, Khoja A, Rashid NH, Ashfaq MA. Outcome of radioactive iodine therapy in Toxic Nodular Goiter in Pakistan. Pak J Med Sci. 2018;34(5):1146-1151.

Author Biographies

Tauseef Ahmad, Dr Ziauddin University Hospital, North Nazimabad Campus, Karachi.

Assistant Professor of Medicine/Endocrinology

Adeel Khoja, Aga Khan University Hospital, Karachi

Instructor Research

Naveed Haroon Rashid, Aga Khan University Hospital, Karachi

Sr. Instructor

Muhammad Areeb Ashfaq, Aga Khan University Hospital, Karachi

Medical Student

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Published

2018-10-02

How to Cite

Ahmad, T., Khoja, A., Rashid, N. H., & Ashfaq, M. A. (2018). Outcome of radioactive iodine therapy in Toxic Nodular Goiter in Pakistan. Pakistan Journal of Medical Sciences, 34(5). https://doi.org/10.12669/pjms.345.15244