The association of symptoms of overactive bladder with pelvic organ prolapse and its improvement after pelvic reconstructive surgery

  • Saida Abrar, DR AKU
  • Raheela Mohsin Rizvi AKU
  • Nida Zahid, DR
Keywords: Overactive bladder (OAB), Pelvic organ prolapse (POP), Pelvic organ prolapse surgery


Objectives: This study asseses the association of overactive bladder symptoms and pelvic organ prolapse severity and evaluates the effect of pelvic reconstructive surgery on overactive bladder (OAB) symptoms in women with pelvic organ prolapse (POP). It also looks into any pre and post-operative factors responsible for persistent postoperative OAB symptoms.

Methods: This was a retrospective cross-sectional study conducted at the Aga Khan University Hospital, Karachi between 1st January 2014 and 31st December 2018. In this study women presenting with POP and concommitent OAB who underwent surgery for site specific defects, measured using Pelvic Organ Prolapse Quantification (POP-Q) staging system. OAB was defined as presence of urinary frequency, urinary urgency incontinence (UUI) and an affirmative response to item #15 and/or item #16 of the Pelvic Floor Distress Inventory (PFDI), which was used both pre and postoperatively. Primary outcome of the study was to find complete resolution or improvement of urinary frequency and UUI on the PFDI, 24 months after surgery. The secondary outcome was to see persistent OAB postoperatively and the factors associated with it.

Results: Overactive bladder (OAB) symptoms improved significantly regardless of the severity of prolapse at 24 months postoperative period. Body mass index (BMI) and postoperative constipation were the only statistically significant variables associated with persistent OAB symptoms postoperatively.

Conclusions: Surgical correction of POP results in significant improvement in symptoms of OAB, in all stages of POP and co-existing OAB. However women with high BMI and post-operative constipation may be prone to persistent frequency and/or UUI.


How to cite this:
Abrar S, Rizvi RM, Zahid N. The association of symptoms of overactive bladder with pelvic organ prolapse and its improvement after pelvic reconstructive surgery. Pak J Med Sci. 2021;37(3):897-902. doi:

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Author Biographies

Saida Abrar, DR, AKU

Dr. Saida Abrar

Clinical Fellow Urogynecology and pelvic reconstructive surgery

Department of Gynecology/Obstetrics

Aga Khan University Hospital, Karachi, Pakistan

Contact number: 92213329356845


Nida Zahid, DR

. Dr. Nida Zahid

Senior Instructor Research

Acting Head of Data Monitoring and Evaluation Division

Office of Academia and Research, Department of Surgery

Aga Khan University Hospital, Karachi, Pakistan


Contact number +923005943858

How to Cite
Abrar, S., Rizvi, R. M., & Zahid, N. (2021). The association of symptoms of overactive bladder with pelvic organ prolapse and its improvement after pelvic reconstructive surgery. Pakistan Journal of Medical Sciences, 37(3).
Original Articles