@article{Wasim_Mushtaq_Wasim_Raana_2021, title={Gynecological malignancies at tertiary care hospital, Pakistan: A five-year review}, volume={37}, url={https://www.pjms.org.pk/index.php/pjms/article/view/3596}, DOI={10.12669/pjms.37.3.3596}, abstractNote={<p><em><strong>Background &amp; Objective:</strong></em> Gynecological malignancies are important cause of female morbidity and mortality. They pose significant burden on health resources in low middle-income countries. Data on presentation and risk factors can help in early identification and reduce this burden. Our objective was to&nbsp;evaluate frequency, stage of presentation and risk factors of gynecological malignancies in a tertiary care setting.</p> <p><em><strong>Methods:</strong></em> It was cross sectional study done in Gynecology Department, Services Institute of Medical Sciences, Services Hospital, Lahore from January 2015- December 2019. The records of the patients were retrospectively reviewed to include all cases of gynecologic malignancies. Demographic information, frequency, risk factors, symptoms, grade and stage of tumor was collected.</p> <p><em><strong>Results:</strong></em> There were 122 patients diagnosed with gynecological malignancy during the study period. Ovarian cancer was seen in 60 (49.18%) patients followed by cervical cancer in 29(23.7%), endometrial cancer 27(22.1%) and vulva 06(4.9%). Mean age for all cancers was 51±12.7 to 55±9.3 except cervical cancer which was seen in 43±8.9 years. Patients with ovarian cancer had significantly more hypertension and diabetes (p&lt;0.05). Heavy menstrual bleeding and postmenopausal bleeding was significantly seen in patients of endometrial and cervical cancer (p&lt;0.05). Abdominal symptoms of pain, mass and distension were seen in patients with ovarian cancer (p&lt;0.05). Majority patients presented in advanced stage. Among ovarian cancer, 52/60(86.6%) were epithelial in origin while 25(86.2%) cervical cancer and all vulva cancers were squamous cell carcinoma.</p> <p><em><strong>Conclusion:</strong></em> Ovarian cancer was commonest gynecological malignancy followed by cervical cancer. Late presentation with advanced stage was seen in majority of all cancers.</p> <p><strong>doi: https://doi.org/10.12669/pjms.37.3.3596</strong></p> <p><em><strong>How to cite this:</strong></em><br>Wasim T, Mushtaq J, Wasim AZ, Gul-e-Raana. Gynecological malignancies at tertiary care hospital, Pakistan: A five-year review. Pak J Med Sci. 2021;37(3):621-627. doi: https://doi.org/10.12669/pjms.37.3.3596</p> <p>This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.</p&gt;}, number={3}, journal={Pakistan Journal of Medical Sciences}, author={Wasim, Tayyiba and Mushtaq, Javeria and Wasim, Ahmad Zunair and Raana, Gul e}, year={2021}, month={Mar.} }